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A temporal hierarchy underpins the transcription factor-DNA interactome of the maize UPR

A temporal hierarchy underpins the transcription factor-DNA interactome of the maize UPR

Posted on December 10, 2020December 21, 2020 by Manuel

Adversarial environmental situations cut back crop productiveness and infrequently improve a load of unfolded or misfolded proteins within the endoplasmic reticulum (ER). This probably deadly situation, often known as ER stress, is buffered by the unfolded protein response (UPR), a set of signaling pathways designed to both get well ER performance or ignite programmed cell loss of life. Regardless of the organic significance of the UPR to the lifetime of the organism, the regulatory transcriptional panorama underpinning ER stress administration is essentially unmapped, particularly in crops. To fill this important information hole, we carried out a large-scale systems-level evaluation of protein-DNA interplay (PDI) community in maize (Zea mays).

Utilizing 23 promoter fragments of six UPR marker genes in a high-throughput enhanced yeast one-hybrid (eY1H) assay, we recognized a extremely interconnected community of 262 transcription elements (TFs) related to important organic traits and 831 PDIs underlying the UPR. We established a temporal hierarchy of TF binding to gene promoters inside the identical household in addition to throughout completely different households of TFs. Cistrome evaluation revealed the dynamic actions of a wide range of cis-regulatory parts (CREs) in ER stress-responsive gene promoters. By integrating the cistrome outcomes right into a TF community evaluation, we mapped a subnetwork of TFs related to a CRE which will contribute to the UPR administration. Lastly, we validated the function of a predicted community hub gene utilizing the Arabidopsis system. The PDIs, TF networks and CREs recognized in our work are foundational assets for understanding transcription regulatory mechanisms within the stress responses and crop enchancment.

Transcription elements are concerned in lots of mobile processes that happen distant from their cognate DNA sequences. The efficiencies of those actions are thus in precept counteracted by excessive binding affinities of the elements to their cognate DNAs. Fashions reminiscent of facilitated diffusion or dissociation deal with this obvious contradiction. We present that the MYC related transcription issue X (MAX) undergoes nanoscale conformational fluctuations within the DNA-bound state, which is according to facilitated dissociation from or diffusion alongside DNA strands by transiently decreasing binding energies. An integrative method involving EPR, NMR, crystallographic and molecular dynamics analyses demonstrates that the N-terminal area of MAX continually opens and closes round a certain DNA ligand thereby dynamically tuning the binding epitope and the mode of interplay.

 

Mycobacteria excises DNA harm in 12- or 13-nucleotide-long oligomers by prokaryotic-type twin incisions and performs transcription-coupled restore

In nucleotide excision restore, cumbersome DNA lesions reminiscent of UV-induced cyclobutane pyrimidine dimers (CPDs) are faraway from the genome by concerted twin incisions bracketing the lesion, adopted by hole filling and ligation. To this point, two twin incision patterns have been found: prokaryotic sort which removes the harm in 11-13 nucleotide-long oligomers and eukaryotic sort which removes the harm in 24-32 nucleotide-long oligomers. Nevertheless, a current examine reported that the UvrC protein of Mycobacterium tuberculosis removes harm in a fashion analogous to yeast and people in a 25-mer oligonucleotide arising from incisions at 15 nucleotides from the three’ finish and 9 nucleotides from the 5′ finish flanking the harm.
To check this mannequin, we used the in vivo excision assay and the XR-seq genome-wide restore mapping technique developed in our lab to find out the restore sample and genome-wide restore map of M. smegmatis We discover that M. smegmatis, which possesses homologues of the E. coli uvrA, B, and C genes, removes CPDs from the genome in a fashion an identical to the prokaryotic sample by incising 7 nucleotides 5′ and three or four nucleotides 3′ to the photoproduct, and performs transcription-coupled restore in a fashion just like E. coli. On the coronary heart of the transcription course of is the particular interplay between transcription elements (TFs) and their goal DNA sequences. A long time of molecular biology analysis have led to unprecedented insights into how TFs entry the genome to manage transcription.
Within the final 20 years, advances in microscopy have enabled scientists so as to add imaging as a strong device in probing two particular points of TF-DNA interactions: construction and dynamics. On this evaluate, we look at how functions of numerous imaging applied sciences can present structural and dynamic data that enhances insights gained from molecular biology assays. As a case examine, we talk about how functions of superior imaging strategies have reshaped our understanding of TF conduct throughout the cell cycle, resulting in a rethinking within the area of mitotic bookmarking.
 A temporal hierarchy underpins the transcription factor-DNA interactome of the maize UPR
A temporal hierarchy underpins the transcription factor-DNA interactome of the maize UPR

A Recurrent Activating Missense Mutation in Waldenström Macroglobulinemia Impacts the DNA Binding of the ETS Transcription Issue SPI1 and Enhances Proliferation.

The ETS-domain transcription elements divide into subfamilies based mostly on protein similarities, DNA-binding sequences, and interplay with cofactors. They’re regulated by extracellular clues and contribute to mobile processes, together with proliferation and transformation. ETS genes are focused via genomic rearrangements in oncogenesis. The PU.1/SPI1 gene is inactivated by level mutations in human myeloid malignancies. We recognized a recurrent somatic mutation (Q226E) in PU.1/SPI1 in Waldenström macroglobulinemia, a B-cell lymphoproliferative dysfunction.
It impacts the DNA-binding affinity of the protein and permits the mutant protein to extra ceaselessly bind and activate promoter areas with respect to wild-type protein. Mutant SPI1 binding at promoters prompts gene units usually promoted by different ETS elements, leading to enhanced proliferation and decreased terminal B-cell differentiation in mannequin cell traces and first samples. In abstract, we describe oncogenic subversion of transcription issue operate via delicate alteration of DNA binding resulting in mobile proliferation and differentiation arrest.

Transcription Factor 25 (TCF25) Antibody

abx340220-100ug Abbexa 100 ug
EUR 469.2

TCF25 Antibody / Transcription factor 25

V9210-100UG NSJ Bioreagents 100ug
EUR 499
Description: Nulp1 (nuclear localized protein 1), also known as TCF25 (transcription factor 25 (basic helix-loop-helix)), Hulp1 or FKSG26, is a 676 amino acid protein that plays a role in cell death. A member of the TCF25 family, Nulp1 utilizes its C-terminus to mediate transcriptional repression of SRF in vitro, and interacts with XIAP. Nulp1 localizes primarily to the nucleus but is also found in cytosol. Widely expressed, Nulp1 is found at high levels in embryonic brain and adult heart. The gene encoding Nulp1 maps to human chromosome 16q24.3, which encodes over 900 genes and comprises nearly 3% of the human genome. The GAN gene is located on chromosome 16 and, with mutation, may lead to giant axonal neuropathy, a nervous system disorder characterized by increasing malfunction with growth. The rare disorder Rubinstein-Taybi syndrome is also associated with chromosome 16, as is Crohn s disease, which is a gastrointestinal inflammatory condition.

TCF25 Antibody / Transcription factor 25

V9210-20UG NSJ Bioreagents 20ug
EUR 219
Description: Nulp1 (nuclear localized protein 1), also known as TCF25 (transcription factor 25 (basic helix-loop-helix)), Hulp1 or FKSG26, is a 676 amino acid protein that plays a role in cell death. A member of the TCF25 family, Nulp1 utilizes its C-terminus to mediate transcriptional repression of SRF in vitro, and interacts with XIAP. Nulp1 localizes primarily to the nucleus but is also found in cytosol. Widely expressed, Nulp1 is found at high levels in embryonic brain and adult heart. The gene encoding Nulp1 maps to human chromosome 16q24.3, which encodes over 900 genes and comprises nearly 3% of the human genome. The GAN gene is located on chromosome 16 and, with mutation, may lead to giant axonal neuropathy, a nervous system disorder characterized by increasing malfunction with growth. The rare disorder Rubinstein-Taybi syndrome is also associated with chromosome 16, as is Crohn s disease, which is a gastrointestinal inflammatory condition.

TCF25 Antibody / Transcription factor 25

V9210SAF-100UG NSJ Bioreagents 100ug
EUR 499
Description: Nulp1 (nuclear localized protein 1), also known as TCF25 (transcription factor 25 (basic helix-loop-helix)), Hulp1 or FKSG26, is a 676 amino acid protein that plays a role in cell death. A member of the TCF25 family, Nulp1 utilizes its C-terminus to mediate transcriptional repression of SRF in vitro, and interacts with XIAP. Nulp1 localizes primarily to the nucleus but is also found in cytosol. Widely expressed, Nulp1 is found at high levels in embryonic brain and adult heart. The gene encoding Nulp1 maps to human chromosome 16q24.3, which encodes over 900 genes and comprises nearly 3% of the human genome. The GAN gene is located on chromosome 16 and, with mutation, may lead to giant axonal neuropathy, a nervous system disorder characterized by increasing malfunction with growth. The rare disorder Rubinstein-Taybi syndrome is also associated with chromosome 16, as is Crohn s disease, which is a gastrointestinal inflammatory condition.

TCF25 Antibody / Transcription factor 25

V9230-100UG NSJ Bioreagents 100ug
EUR 499
Description: Nulp1 (nuclear localized protein 1), also known as TCF25 (transcription factor 25 (basic helix-loop-helix)), Hulp1 or FKSG26, is a 676 amino acid protein that plays a role in cell death. A member of the TCF25 family, Nulp1 utilizes its C-terminus to mediate transcriptional repression of SRF in vitro, and interacts with XIAP. Nulp1 localizes primarily to the nucleus but is also found in cytosol. Widely expressed, Nulp1 is found at high levels in embryonic brain and adult heart. The gene encoding Nulp1 maps to human chromosome 16q24.3, which encodes over 900 genes and comprises nearly 3% of the human genome. The GAN gene is located on chromosome 16 and, with mutation, may lead to giant axonal neuropathy, a nervous system disorder characterized by increasing malfunction with growth. The rare disorder Rubinstein-Taybi syndrome is also associated with chromosome 16, as is Crohn s disease, which is a gastrointestinal inflammatory condition.

TCF25 Antibody / Transcription factor 25

V9230-20UG NSJ Bioreagents 20ug
EUR 219
Description: Nulp1 (nuclear localized protein 1), also known as TCF25 (transcription factor 25 (basic helix-loop-helix)), Hulp1 or FKSG26, is a 676 amino acid protein that plays a role in cell death. A member of the TCF25 family, Nulp1 utilizes its C-terminus to mediate transcriptional repression of SRF in vitro, and interacts with XIAP. Nulp1 localizes primarily to the nucleus but is also found in cytosol. Widely expressed, Nulp1 is found at high levels in embryonic brain and adult heart. The gene encoding Nulp1 maps to human chromosome 16q24.3, which encodes over 900 genes and comprises nearly 3% of the human genome. The GAN gene is located on chromosome 16 and, with mutation, may lead to giant axonal neuropathy, a nervous system disorder characterized by increasing malfunction with growth. The rare disorder Rubinstein-Taybi syndrome is also associated with chromosome 16, as is Crohn s disease, which is a gastrointestinal inflammatory condition.

TCF25 Antibody / Transcription factor 25

V9230SAF-100UG NSJ Bioreagents 100ug
EUR 499
Description: Nulp1 (nuclear localized protein 1), also known as TCF25 (transcription factor 25 (basic helix-loop-helix)), Hulp1 or FKSG26, is a 676 amino acid protein that plays a role in cell death. A member of the TCF25 family, Nulp1 utilizes its C-terminus to mediate transcriptional repression of SRF in vitro, and interacts with XIAP. Nulp1 localizes primarily to the nucleus but is also found in cytosol. Widely expressed, Nulp1 is found at high levels in embryonic brain and adult heart. The gene encoding Nulp1 maps to human chromosome 16q24.3, which encodes over 900 genes and comprises nearly 3% of the human genome. The GAN gene is located on chromosome 16 and, with mutation, may lead to giant axonal neuropathy, a nervous system disorder characterized by increasing malfunction with growth. The rare disorder Rubinstein-Taybi syndrome is also associated with chromosome 16, as is Crohn s disease, which is a gastrointestinal inflammatory condition.

anti-Transcription factor 25

YF-PA17698 Abfrontier 50 ul
EUR 435.6
Description: Mouse polyclonal to Transcription factor 25

Human Transcription factor 25, TCF25 ELISA KIT

ELI-41832h Lifescience Market 96 Tests
EUR 988.8

Mouse Transcription factor 25, Tcf25 ELISA KIT

ELI-41954m Lifescience Market 96 Tests
EUR 1038

MTBK_20640-25

AR02-P0011-25 Abfrontier 25ug
EUR 567.6

Rv0351 (GrpE)-25

AR02-P0003-25 Abfrontier 25ug
EUR 151.2

Rv1009 (RpfB)-25

AR02-P0006-25 Abfrontier 25ug
EUR 567.6

Rv2450c (RpfE)-25

AR02-P0007-25 Abfrontier 25ug
EUR 567.6

Rv3875 (esxA)-25

AR02-P0008-25 Abfrontier 25ug
EUR 567.6

Rv2031c(HspX)-25

AR02-P0009-25 Abfrontier 25ug
EUR 567.6

Rv3131 (NfnB)-25

AR02-P0010-25 Abfrontier 25ug
EUR 567.6

Transcription factor Sp1 Antibody

39381-100ul SAB 100ul
EUR 468

Transcription factor E3 antibody

22888-100ul SAB 100ul
EUR 468

Transcription factor Sp1 Antibody

abx037665-100ug Abbexa 100 ug
EUR 469.2

Transcription factor p65 Antibody

20-abx110271 Abbexa
  • EUR 493.20
  • EUR 2214.00
  • EUR 718.80
  • EUR 218.40
  • EUR 360.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

Sp1 Transcription Factor Antibody

20-abx115746 Abbexa
  • EUR 878.40
  • EUR 477.60
  • 150 ul
  • 50 ul

Sp6 Transcription Factor Antibody

20-abx115749 Abbexa
  • EUR 878.40
  • EUR 477.60
  • 150 ul
  • 50 ul

Transcription Factor 12 Antibody

20-abx116153 Abbexa
  • EUR 878.40
  • EUR 477.60
  • 150 ul
  • 50 ul

Transcription Factor Cp2 Antibody

20-abx116163 Abbexa
  • EUR 878.40
  • EUR 477.60
  • 150 ul
  • 50 ul

Transcription factor IID Antibody

abx430011-200ul Abbexa 200 ul
EUR 460.8

Transcription factor E2F4 Antibody

abx431012-200ul Abbexa 200 ul
EUR 460.8

Transcription factor E2F1 Antibody

abx433397-200ul Abbexa 200 ul
EUR 460.8

26795 25 CLOSURE NTRL 25MM

26795-25 CORNING 50/pk
EUR 115.2
Description: Disposable Screw Cap Culture Tubes; Poly Closures

Amyloid Beta-peptide (25-35) (human)

A1039-25 ApexBio 25 mg
EUR 606
Description: Met-Leu-Gly-Ile-Ile-Ala-Gly-Lys-Asn-Ser-GlyAmyloid- ? (A?) peptide is commonly found in human Alzheimer?s disease (AD) brain and is the main component of Alzheimer amyloid plaques. The predominant forms of A? in the human brain are A? (1-40) and A? (1-42).

Express Plasmid Maxiprep Kit (25 min)

K1324-25 Biovision
EUR 732

Express Plasmid Midiprep Kit (25 min)

K1323-25 Biovision
EUR 561.6

Rv2769c (PE27 protein)-25

AR02-P0001-25 Abfrontier 25ug
EUR 243.6

2.5x14 cellogel 250µ (25)

EHCA1200-ST06-25 Consort ea
EUR 45.6

2.5x14 cellogel 200µ (25)

EHCA1200-ST07-25 Consort ea
EUR 45.6

2.5x17 cellogel 250µ (25)

EHCA1200-ST11-25 Consort ea
EUR 49.2

2.5x17 cellogel 200µ (25)

EHCA1200-ST12-25 Consort ea
EUR 49.2

5.7x13 cellogel 250µ (25)

EHCA1200-ST29U-25 Consort ea
EUR 72

5.7x14 cellogel 250µ (25)

EHCA1200-ST31-25 Consort ea
EUR 63.6

5.7x14 cellogel 200µ (25)

EHCA1200-ST32-25 Consort ea
EUR 63.6

5.7x14 cellogel 500µ (25)

EHCA1200-ST34-25 Consort ea
EUR 72

Transcription factor p65 Polyclonal Antibody

42406-100ul SAB 100ul
EUR 399.6

Transcription Factor 4 (TCF4) Antibody

abx149958-100ug Abbexa 100 ug
EUR 526.8

Transcription Factor P65 (RELA) Antibody

20-abx159676 Abbexa
  • EUR 326.40
  • EUR 276.00
  • 100 ug
  • 50 ug

Transcription Factor P65 (RELA) Antibody

20-abx159677 Abbexa
  • EUR 326.40
  • EUR 276.00
  • 100 ug
  • 50 ug

Transcription Factor MafB (MAFB) Antibody

20-abx135995 Abbexa
  • EUR 493.20
  • EUR 710.40
  • EUR 218.40
  • EUR 376.80
  • 100 ul
  • 200 ul
  • 20 ul
  • 50 ul

Transcription Factor 4 (TCF4) Antibody

20-abx141590 Abbexa
  • EUR 444.00
  • EUR 727.20
  • EUR 360.00
  • 100 ul
  • 200 ul
  • 50 ul

Transcription Factor SP1 (SP1) Antibody

20-abx134667 Abbexa
  • EUR 360.00
  • EUR 526.80
  • EUR 226.80
  • 100 ul
  • 200 ul
  • 30 ul

Transcription Factor 20 (TCF20) Antibody

20-abx102490 Abbexa
  • EUR 493.20
  • EUR 159.60
  • EUR 1362.00
  • EUR 661.20
  • EUR 376.80
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Transcription Factor 20 (TCF20) Antibody

20-abx102491 Abbexa
  • EUR 493.20
  • EUR 159.60
  • EUR 1362.00
  • EUR 661.20
  • EUR 376.80
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Transcription Factor 20 (TCF20) Antibody

20-abx102492 Abbexa
  • EUR 493.20
  • EUR 159.60
  • EUR 1362.00
  • EUR 661.20
  • EUR 376.80
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Transcription Factor 20 (TCF20) Antibody

20-abx102493 Abbexa
  • EUR 493.20
  • EUR 159.60
  • EUR 1362.00
  • EUR 661.20
  • EUR 376.80
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Transcription Factor Sp3 (SP3) Antibody

abx037814-100ug Abbexa 100 ug
EUR 469.2

Transcription Factor P65 (NFKB3) Antibody

abx037885-100ug Abbexa 100 ug
EUR 469.2

Transcription Factor SP1 (SP1) Antibody

abx037890-100ug Abbexa 100 ug
EUR 469.2

Transcription Factor P65 (NFKB3) Antibody

abx038310-100ug Abbexa 100 ug
EUR 469.2

Transcription Factor Sp3 (SP3) Antibody

abx038329-100ug Abbexa 100 ug
EUR 469.2

Transcription Factor 19 (TCF19) Antibody

20-abx004702 Abbexa
  • EUR 493.20
  • EUR 710.40
  • EUR 218.40
  • EUR 376.80
  • 100 ul
  • 200 ul
  • 20 ul
  • 50 ul

Transcription Factor EB (TFEB) Antibody

20-abx005518 Abbexa
  • EUR 493.20
  • EUR 710.40
  • EUR 218.40
  • EUR 376.80
  • 100 ul
  • 200 ul
  • 20 ul
  • 50 ul

Transcription Factor P65 (RELA) Antibody

20-abx000722 Abbexa
  • EUR 493.20
  • EUR 710.40
  • 100 ul
  • 200 ul

Transcription Factor 4 (TCF4) Antibody

20-abx001055 Abbexa
  • EUR 493.20
  • EUR 710.40
  • EUR 218.40
  • EUR 376.80
  • 100 ul
  • 200 ul
  • 20 ul
  • 50 ul

Transcription Factor 7 (TCF7) Antibody

20-abx002222 Abbexa
  • EUR 493.20
  • EUR 710.40
  • EUR 218.40
  • EUR 376.80
  • 100 ul
  • 200 ul
  • 20 ul
  • 50 ul

Transcription Factor SP1 (SP1) Antibody

20-abx002376 Abbexa
  • EUR 493.20
  • EUR 710.40
  • 100 ul
  • 200 ul

Transcription Factor Maf (MAF) Antibody

20-abx002609 Abbexa
  • EUR 493.20
  • EUR 710.40
  • EUR 218.40
  • EUR 376.80
  • 100 ul
  • 200 ul
  • 20 ul
  • 50 ul

Transcription Factor 12 (TCF12) Antibody

20-abx003060 Abbexa
  • EUR 493.20
  • EUR 710.40
  • EUR 218.40
  • EUR 376.80
  • 100 ul
  • 200 ul
  • 20 ul
  • 50 ul

Transcription Factor EC (TFEC) Antibody

20-abx003378 Abbexa
  • EUR 493.20
  • EUR 710.40
  • 100 ul
  • 200 ul

Transcription Factor CP2 (TFCP2) Antibody

20-abx004254 Abbexa
  • EUR 493.20
  • EUR 710.40
  • EUR 218.40
  • EUR 376.80
  • 100 ul
  • 200 ul
  • 20 ul
  • 50 ul

Transcription Factor Maf (MAF) Antibody

20-abx009013 Abbexa
  • EUR 360.00
  • EUR 526.80
  • EUR 226.80
  • 100 ul
  • 200 ul
  • 30 ul

Transcription Factor EB (TFEB) Antibody

20-abx008549 Abbexa
  • EUR 360.00
  • EUR 526.80
  • EUR 226.80
  • 100 ul
  • 200 ul
  • 30 ul

Twist Transcription Factor (TWIST) Antibody

20-abx008603 Abbexa
  • EUR 360.00
  • EUR 526.80
  • EUR 226.80
  • 100 ul
  • 200 ul
  • 30 ul

Transcription Factor 19 (TCF19) Antibody

20-abx008655 Abbexa
  • EUR 360.00
  • EUR 526.80
  • EUR 226.80
  • 100 ul
  • 200 ul
  • 30 ul

Transcription Factor 7 (TCF7) Antibody

20-abx008657 Abbexa
  • EUR 360.00
  • EUR 526.80
  • EUR 226.80
  • 100 ul
  • 200 ul
  • 30 ul

Transcription Factor 7 (TCF7) Antibody

20-abx119401 Abbexa
  • EUR 376.80
  • EUR 117.60
  • EUR 477.60
  • EUR 594.00
  • 100 ug
  • 10 ug
  • 200 ug
  • 300 µg

Transcription Factor P65 (RELA) Antibody

20-abx125055 Abbexa
  • EUR 594.00
  • EUR 844.80
  • EUR 427.20
  • 100 ul
  • 200 ul
  • 50 ul

Transcription Factor P65 (RELA) Antibody

20-abx125390 Abbexa
  • EUR 710.40
  • EUR 1028.40
  • EUR 493.20
  • 100 ul
  • 200 ul
  • 50 ul

Transcription factor p65 Antibody (HRP)

20-abx108816 Abbexa
  • EUR 493.20
  • EUR 2214.00
  • EUR 718.80
  • EUR 218.40
  • EUR 360.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

Transcription Factor BTF3 (BTF3) Antibody

20-abx110270 Abbexa
  • EUR 493.20
  • EUR 2214.00
  • EUR 718.80
  • EUR 218.40
  • EUR 360.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

Transcription factor PU.1 Antibody

20-abx110272 Abbexa
  • EUR 493.20
  • EUR 2214.00
  • EUR 718.80
  • EUR 218.40
  • EUR 360.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

Transcription factor SOX-2 Antibody

20-abx110273 Abbexa
  • EUR 493.20
  • EUR 2214.00
  • EUR 718.80
  • EUR 218.40
  • EUR 360.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

Transcription termination factor Rho Antibody

20-abx110544 Abbexa
  • EUR 493.20
  • EUR 2214.00
  • EUR 718.80
  • EUR 218.40
  • EUR 360.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

Transcription termination factor Rho Antibody

20-abx110576 Abbexa
  • EUR 493.20
  • EUR 2214.00
  • EUR 718.80
  • EUR 218.40
  • EUR 360.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

Transcription Factor Dp1 (TFDP1) Antibody

20-abx130969 Abbexa
  • EUR 543.60
  • EUR 159.60
  • EUR 1562.40
  • EUR 744.00
  • EUR 410.40
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Transcription factor p65 Antibody (Biotin)

20-abx105981 Abbexa
  • EUR 493.20
  • EUR 2214.00
  • EUR 718.80
  • EUR 218.40
  • EUR 360.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

Transcription factor p65 Antibody (FITC)

20-abx107396 Abbexa
  • EUR 493.20
  • EUR 2214.00
  • EUR 718.80
  • EUR 218.40
  • EUR 360.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

Transcription Factor Dp-1 Antibody

20-abx116164 Abbexa
  • EUR 878.40
  • EUR 477.60
  • 150 ul
  • 50 ul

Transcription Factor Eb (TFEB) Antibody

20-abx116166 Abbexa
  • EUR 878.40
  • EUR 477.60
  • 150 ul
  • 50 ul

Transcription Factor Ec (TFEC) Antibody

20-abx116167 Abbexa
  • EUR 878.40
  • EUR 477.60
  • 150 ul
  • 50 ul

Transcription Factor P65 (RELA) Antibody

20-abx126473 Abbexa
  • EUR 493.20
  • EUR 710.40
  • EUR 218.40
  • EUR 376.80
  • 100 ul
  • 200 ul
  • 20 ul
  • 50 ul

Transcription Factor P65 (RELA) Antibody

20-abx126474 Abbexa
  • EUR 493.20
  • EUR 710.40
  • EUR 218.40
  • EUR 376.80
  • 100 ul
  • 200 ul
  • 20 ul
  • 50 ul

Transcription Factor EB (TFEB) Antibody

20-abx126691 Abbexa
  • EUR 493.20
  • EUR 710.40
  • EUR 218.40
  • EUR 376.80
  • 100 ul
  • 200 ul
  • 20 ul
  • 50 ul

Mitochondrial Transcription Termination Factor Antibody

20-abx113821 Abbexa
  • EUR 878.40
  • EUR 477.60
  • 150 ul
  • 50 ul

Transcription Factor Maf (MAF) Antibody

20-abx013321 Abbexa
  • EUR 376.80
  • EUR 117.60
  • EUR 477.60
  • EUR 594.00
  • 100 ug
  • 10 ug
  • 200 ug
  • 300 µg

Transcription Factor EB (TFEB) Antibody

abx018172-100ug Abbexa 100 ug
EUR 410.4

Transcription Factor CP2 (TFCP2) Antibody

abx018344-100ug Abbexa 100 ug
EUR 460.8

Transcription Factor CP2 (TFCP2) Antibody

abx018345-100ug Abbexa 100 ug
EUR 460.8

Transcription Factor P65 (RELA) Antibody

abx033005-400ul Abbexa 400 ul
EUR 627.6

Transcription Factor P65 (RELA) Antibody

abx033005-80l Abbexa 80 µl
EUR 343.2

Transcription Factor MafB (MAFB) Antibody

abx026673-400ul Abbexa 400 ul
EUR 627.6

Transcription Factor MafB (MAFB) Antibody

abx026673-80l Abbexa 80 µl
EUR 343.2

Transcription Factor Sp3 (SP3) Antibody

abx028040-400ul Abbexa 400 ul
EUR 627.6

Transcription Factor Sp3 (SP3) Antibody

abx028040-80l Abbexa 80 µl
EUR 343.2

Transcription Factor 12 (TCF12) Antibody

abx028344-400ul Abbexa 400 ul
EUR 627.6

Transcription Factor 12 (TCF12) Antibody

abx028344-80l Abbexa 80 µl
EUR 343.2

Transcription Factor MafG (MAFG) Antibody

abx029789-400ul Abbexa 400 ul
EUR 627.6

Transcription Factor MafG (MAFG) Antibody

abx029789-80l Abbexa 80 µl
EUR 343.2

Transcription Factor EC (TFEC) Antibody

abx031036-400ul Abbexa 400 ul
EUR 627.6

Transcription Factor EC (TFEC) Antibody

abx031036-80l Abbexa 80 µl
EUR 343.2

Transcription Factor P65 (RELA) Antibody

abx031232-400ul Abbexa 400 ul
EUR 627.6

Transcription Factor P65 (RELA) Antibody

abx031232-80l Abbexa 80 µl
EUR 343.2

Transcription Factor P65 (RELA) Antibody

abx031234-400ul Abbexa 400 ul
EUR 627.6

Transcription Factor P65 (RELA) Antibody

abx031234-80l Abbexa 80 µl
EUR 343.2

Transcription Factor P65 (RELA) Antibody

abx031446-400ul Abbexa 400 ul
EUR 627.6

Transcription Factor P65 (RELA) Antibody

abx031446-80l Abbexa 80 µl
EUR 343.2

Transcription Factor BTF3 (BTF3) Antibody

abx026082-400ul Abbexa 400 ul
EUR 627.6

Transcription Factor BTF3 (BTF3) Antibody

abx026082-80l Abbexa 80 µl
EUR 343.2

Transcription Factor SP1 (SP1) Antibody

abx026270-400ul Abbexa 400 ul
EUR 627.6

Transcription Factor SP1 (SP1) Antibody

abx026270-80l Abbexa 80 µl
EUR 343.2

Transcription Factor 21 (TCF21) Antibody

abx026335-400ul Abbexa 400 ul
EUR 627.6

Transcription Factor 21 (TCF21) Antibody

abx026335-80l Abbexa 80 µl
EUR 343.2

SP2 Transcription Factor (Sp2) Antibody

abx037457-100ug Abbexa 100 ug
EUR 469.2

Transcription Factor 7 (TCF7) Antibody

abx025094-400ul Abbexa 400 ul
EUR 627.6

Transcription Factor 7 (TCF7) Antibody

abx025094-80l Abbexa 80 µl
EUR 343.2

Twist Transcription Factor (TWIST) Antibody

20-abx178778 Abbexa
  • EUR 510.00
  • EUR 159.60
  • EUR 1446.00
  • EUR 693.60
  • EUR 393.60
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

YY1 Transcription Factor (YY1) Antibody

20-abx178954 Abbexa
  • EUR 1446.00
  • EUR 693.60
  • 1 mg
  • 200 ug

Transcription Factor EB (TFEB) Antibody

20-abx320372 Abbexa
  • EUR 360.00
  • EUR 292.80
  • 100 ul
  • 50 ul

Transcription Factor CP2 (TFCP2) Antibody

20-abx320668 Abbexa
  • EUR 526.80
  • EUR 393.60
  • 100 ul
  • 50 ul

Transcription Factor 12 (TCF12) Antibody

20-abx321364 Abbexa
  • EUR 360.00
  • EUR 292.80
  • 100 ul
  • 50 ul

Transcription Factor EB (TFEB) Antibody

20-abx322154 Abbexa
  • EUR 360.00
  • EUR 292.80
  • 100 ul
  • 50 ul

Transcription Factor CP2 (TFCP2) Antibody

20-abx322362 Abbexa
  • EUR 526.80
  • EUR 393.60
  • 100 ul
  • 50 ul

Transcription Factor 19 (TCF19) Antibody

20-abx322757 Abbexa
  • EUR 526.80
  • EUR 393.60
  • 100 ul
  • 50 ul

Transcription Factor Maf (MAF) Antibody

abx332666-100ul Abbexa 100 ul
EUR 510

Transcription Factor 15 (TCF15) Antibody

20-abx334114 Abbexa
  • EUR 493.20
  • EUR 2214.00
  • EUR 718.80
  • EUR 218.40
  • EUR 360.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

Transcription Factor Maf (MAF) Antibody

20-abx334117 Abbexa
  • EUR 493.20
  • EUR 2214.00
  • EUR 718.80
  • EUR 218.40
  • EUR 360.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

Transcription Factor Dp1 (TFDP1) Antibody

abx330538-100ul Abbexa 100 ul
EUR 510

Transcription Factor Dp1 (TFDP1) Antibody

abx331429-100ul Abbexa 100 ul
EUR 510

Transcription Factor MafB (MAFB) Antibody

20-abx216646 Abbexa
  • EUR 510.00
  • EUR 410.40
  • 100 ug
  • 50 ug

SP2 Transcription Factor (SP2) Antibody

abx218725-100ug Abbexa 100 ug
EUR 526.8

Transcription Factor Sp5 (SP5) Antibody

20-abx219103 Abbexa
  • EUR 510.00
  • EUR 410.40
  • 100 ug
  • 50 ug

Transcription Factor 4 (TCF4) Antibody

abx224361-100ug Abbexa 100 ug
EUR 493.2

Transcription Factor 4 (TCF4) Antibody

abx224463-100ug Abbexa 100 ug
EUR 493.2

Transcription Factor E2F3 (E2F3) Antibody

20-abx301026 Abbexa
  • EUR 493.20
  • EUR 2214.00
  • EUR 718.80
  • EUR 218.40
  • EUR 360.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

SP2 Transcription Factor (SP2) Antibody

20-abx249435 Abbexa
  • EUR 376.80
  • EUR 117.60
  • EUR 477.60
  • EUR 594.00
  • 100 ug
  • 10 ug
  • 200 ug
  • 300 µg

Transcription Factor EB (TFEB) Antibody

20-abx302280 Abbexa
  • EUR 493.20
  • EUR 2214.00
  • EUR 718.80
  • EUR 218.40
  • EUR 360.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug
×
SIGNIFICANCE: The demonstration {that a} somatic level mutation suggestions the stability of genome-binding sample gives a mechanistic paradigm for the way missense mutations in transcription issue genes could also be oncogenic in human tumors.This text is highlighted within the In This Difficulty characteristic, p. 681.

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Recent Posts

  • All types of Research and Publication (including in Diabetes) have shown a healthy rising trend from India in the last decade
  • Cepheid GeneXpert NATtrol
  • Forkhead transcription factor O1 (FoxO1) in torafugu pufferfish Takifugu rubripes: Molecular cloning, in vitro DNA binding, and target gene screening in fish metagenome
  • A Simple Fluorescence Microplate Assay to Monitor RNA-DNA Hybrid Unwinding by the Bacterial Transcription Termination Factor Rho
  • MYB_SH[AL]QKY[RF] transcription factors MdLUX and MdPCL-like promote anthocyanin accumulation through DNA hypomethylation and MdF3H activation in apple
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